Heightman, M: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

The discovery and optimisation of benzazepine sulfonamide and sulfones as potent agonists of the motilin receptor

James M. Bailey, Jackie S. Scott, Jonathan B. Basilla, Victoria J. Bolton, Izzy Boyfield, David G. Evans, Etienne Fleury, Tom D. Heightman, Emma M. Jarvie, Kirk Lawless, Kim L. Matthews, Fiona McKay,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 1.21 MB

english, 2009

2

Television reception 1925Â¿1975

Heightman, D.W.

Journal:

Radio and Electronic Engineer

Year:

1975

Language:

english

File:

PDF, 3.24 MB

english, 1975

3

âLong-COVIDâ: a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19

Mandal, Swapna, Barnett, Joseph, Brill, Simon E, Brown, Jeremy S, Denneny, Emma K, Hare, Samanjit S, Heightman, Melissa, Hillman, Toby E, Jacob, Joseph, Jarvis, Hannah C, Lipman, Marc C I, Naidu, Sind

Journal:

Year:

2020

File:

PDF, 384 KB

2020

4

Neue Erkenntnisse über Hemmung, Struktur und Mechanismus konfigurationserhaltender Glycosidasen

Tom D. Heightman, Andrea T. Vasella

Journal:

Angewandte Chemie

Year:

1999

Language:

german

File:

PDF, 764 KB

german, 1999

5

Recent Insights into Inhibition, Structure, and Mechanism of Configuration-Retaining Glycosidases

Tom D. Heightman, Andrea T. Vasella

Journal:

Angewandte Chemie International Edition

Year:

1999

Language:

english

File:

PDF, 744 KB

english, 1999

6

Inhibition of Glycosidases by Lactam Oximes: Influence of the Aglycon in Disaccharide Analogues

Stefan Vonhoff, Tom D. Heightman, Andrea Vasella

Journal:

Helvetica Chimica Acta

Year:

1998

Language:

english

File:

PDF, 231 KB

english, 1998

7

ChemInform Abstract: Synthesis of Fused Triazoles as Probes for the Active Site of Retaining β-Glycosidases: From Which Direction Is the Glycoside Protonated?

T. D. HEIGHTMAN, M. LOCATELLI, A. VASELLA

Journal:

Year:

1997

File:

PDF, 29 KB

1997

8

ChemInform Abstract: Diastereoselectivity in the Alkylations of Bicyclic Piperidinones.

C. E. MILLS, T. D. HEIGHTMAN, S. A. HERMITAGE, M. G. MOLONEY, G. A. WOODS

Journal:

Year:

1998

File:

PDF, 35 KB

1998

9

ChemInform Abstract: Recent Insights into Inhibition, Structure, and Mechanism of Configuration-Retaining Glycosidases

Tom D. Heightman, Andrea T. Vasella

Journal:

Year:

1999

File:

PDF, 25 KB

1999

10

Enantiopure Bicyclic Piperidinones: Stereoselectivity in Lactam Enolate Alkylations.

Andrew G. Brewster, Simon Broady, Catherine E. Davies, Thomas D. Heightman, Stephen A. Hermitage, Mark Hughes, Mark G. Moloney, Gordon Woods

Journal:

Year:

2004

File:

PDF, 206 KB

2004

11

Discovery of a Potent and Selective 5-ht5A Receptor Antagonist (I) by High-Throughput Chemistry.

David F. Corbett, Tom D. Heightman, Stephen F. Moss, Steven M. Bromidge, Sara A. Coggon, Mark J. Longley, Ana Maria Roa, Jennifer A. Williams, David R. Thomas

Journal:

Year:

2005

File:

PDF, 9 KB

2005

12

8-Piperazinyl-2,3-dihydropyrrolo[3,2-g]isoquinolines: Potent, Selective, Orally Bioavailable 5-HT1 Receptor Ligands.

Tom D. Heightman, et al. et al.

Journal:

Year:

2005

File:

PDF, 19 KB

2005

13

Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds

Kai-Hsuan Chang, Dr. Oliver N. F. King, Dr. Anthony Tumber, Dr. Esther C. Y. Woon, Dr. Tom D. Heightman, Dr. Michael A. McDonough, Prof. Dr. Christopher J. Schofield, Dr. Nathan R. Rose

Journal:

Year:

2011

Language:

english

File:

PDF, 711 KB

english, 2011

14

Synthesis of Galactose- and N-Acetylglucosamine-Derived Tetrazoles and their evaluation as β-glycosidase inhibitors

Thomas D. Heightman, Philipp Ermert, Daniela Klein, Andrea Vasella

Journal:

Helvetica Chimica Acta

Year:

1995

Language:

english

File:

PDF, 1.33 MB

english, 1995

15

Synthesis of Fused Triazoles as Probes for the Active Site of Retaining β-Glycosidases: From Which Direction Is the Glycoside Protonated?

Tom D. Heightman, Monica Locatelli, Andrea Vasella

Journal:

Helvetica Chimica Acta

Year:

1996

Language:

english

File:

PDF, 712 KB

english, 1996

16

Cooperative Interactions of the Catalytic Nucleophile and the Catalytic Acid in the Inhibition of β-Glycosidases. Calculations and their validation by comparative kinetic and structural studies of the inhibition of glycogen phosphorylase b

Tom D. Heightman, Andrea Vasella, Katerina E. Tsitsanou, Spyros E. Zographos, Vicky T. Skamnaki, Nikos G. Oikonomakos

Journal:

Helvetica Chimica Acta

Year:

1998

Language:

english

File:

PDF, 1.14 MB

english, 1998

17

Identification of small molecule agonists of the motilin receptor

Tom D. Heightman, Elizabeth Conway, David F. Corbett, Gregor J. Macdonald, Geoffrey Stemp, Susan M. Westaway, Paolo Celestini, Stefania Gagliardi, Mauro Riccaboni, Silvano Ronzoni, Kalindi Vaidya, Sha

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 220 KB

english, 2008

18

Development of homogeneous luminescence assays for histone demethylase catalysis and binding

Akane Kawamura, Anthony Tumber, Nathan R. Rose, Oliver N.F. King, Michelle Daniel, Udo Oppermann, Tom D. Heightman, Christopher Schofield

Journal:

Analytical Biochemistry

Year:

2010

Language:

english

File:

PDF, 1.13 MB

english, 2010

19

Discovery of a potent and selective 5-ht5A receptor antagonist by high-throughput chemistry

David F. Corbett, Tom D. Heightman, Stephen F. Moss, Steven M. Bromidge, Sara A. Coggon, Mark J. Longley, Ana Maria Roa, Jennifer A. Williams, David R. Thomas

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 679 KB

english, 2005

20

8-Piperazinyl-2,3-dihydropyrrolo[3,2-g]isoquinolines: Potent, selective, orally bioavailable 5-HT1 receptor ligands

Tom D. Heightman, Laramie M. Gaster, Sarah L. Pardoe, Jean-Pierre Pilleux, Michael S. Hadley, Derek N. Middlemiss, Gary W. Price, Claire Roberts, Claire M. Scott, Jeannette M. Watson, Laurie J. Gordon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 171 KB

english, 2005

21

Potent achiral agonists of the ghrelin (growth hormone secretagogue) receptor. Part I: Lead identification

Tom D. Heightman, Jackie S. Scott, Mark Longley, Vincent Bordas, David K. Dean, Richard Elliott, Gail Hutley, Jason Witherington, Lee Abberley, Barry Passingham, Manuela Berlanga, Maite de los Frailes

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 138 KB

english, 2007

22

The discovery of biaryl carboxamides as novel small molecule agonists of the motilin receptor

Susan M. Westaway, Samantha L. Brown, Elizabeth Conway, Tom D. Heightman, Christopher N. Johnson, Kate Lapsley, Gregor J. Macdonald, David T. MacPherson, Darren J. Mitchell, James W. Myatt, Jon T. Sea

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 236 KB

english, 2008

23

Diastereoselectivity in the alkylations of bicyclic piperidinones

Catherine E. Mills (née Davis), Thomas D. Heightman, Stephen A. Hermitage, Mark G. Moloney, Gordon A. Woods

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 260 KB

english, 1998

24

Novel (4-piperazin-1-ylquinolin-6-yl) arylsulfonamides with high affinity and selectivity for the 5-HT6 receptor

Steven M Bromidge, Kerry Griffith, Tom D Heightman, Andrew Jennings, Frank D King, Stephen F Moss, Helen Newman, Graham Riley, Carol Routledge, Halina T Serafinowska, David R Thomas

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 123 KB

english, 2001

25

Nonenzymatic biotinylation of histone H2A

Shannon Healy, Tom D. Heightman, Laura Hohmann, David Schriemer, Roy A. Gravel

Journal:

Protein Science

Year:

2009

Language:

english

File:

PDF, 738 KB

english, 2009

26

Tropospheric Propagation on Lower Radio Frequencies

HEIGHTMAN, D. W.

Journal:

Year:

1949

File:

PDF, 205 KB

1949

27

SB-272183, a selective 5-HT1A, 5-HT1B and 5-HT1D receptor antagonist in native tissue

J Watson, C Roberts, C Scott, I Kendall, L Collin, N C Day, M H Harries, E Soffin, C H Davies, A D Randall, T Heightman, L Gaster, P Wyman, C Parker, G W Price, D N Middlemiss

Journal:

British Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 419 KB

english, 2001

28

A Selective Inhibitor and Probe of the Cellular Functions of Jumonji C Domain-Containing Histone Demethylases

Luo, Xuelai, Liu, Yongxiang, Kubicek, Stefan, Myllyharju, Johanna, Tumber, Anthony, Ng, Stanley, Che, Ka Hing, Podoll, Jessica, Heightman, Tom D., Oppermann, Udo

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 3.76 MB

english, 2011

29

Epigenetic-Targeted Drug Discovery: From the Guest Editors

Heightman, T., Pope, A.

Journal:

Journal of Biomolecular Screening

Year:

2011

Language:

english

File:

PDF, 285 KB

english, 2011

30

Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates

Thalhammer, Armin, Mecinović, Jasmin, Loenarz, Christoph, Tumber, Anthony, Rose, Nathan R., Heightman, Tom D., Schofield, Christopher J.

Journal:

Organic & Biomolecular Chemistry

Year:

2010

Language:

english

File:

PDF, 410 KB

english, 2010

31

ChemInform Abstract: Convenient Preparations of Racemic and Enantiopure Methyl 6- Oxopipecolate.

C. E. DAVIES, T. D. HEIGHTMAN, S. A. HERMITAGE, M. G. MOLONEY

Journal:

Year:

1996

File:

PDF, 29 KB

1996

32

High-resolution native and complex structures of thermostable β-mannanase from Thermomonospora fusca – substrate specificity in glycosyl hydrolase family 5

Mark Hilge, Sergio M Gloor, Wojciech Rypniewski, Oliver Sauer, Tom D Heightman, Wolfgang Zimmermann, Kaspar Winterhalter, Klaus Piontek

Journal:

Year:

1998

Language:

english

File:

PDF, 954 KB

english, 1998

33

A High-Performance Automatic Color Camera

Heightman, A.N.

Journal:

IEEE Transactions on Broadcasting

Year:

1972

Language:

english

File:

PDF, 9.11 MB

english, 1972

34

SS3-7 Transcriptional regulation of interferon stimulated genes: Role of chromatin binding protein Brd4

Mira Patel, Maxime Debrosse, Matthew Smith, Anup Dey, WalterHuynh, Tomohiko Tamura, Tom Heightman, Keiko Ozato

Journal:

Year:

2010

Language:

english

File:

PDF, 40 KB

english, 2010

35

O029 Chromatin exchange in interferon induced transcription

K. Ozato, N. Sarai, M. Patel, M. Debrosse, T. Heightman, T. Tamura, K. Ura

Journal:

Year:

2012

Language:

english

File:

PDF, 133 KB

english, 2012

36

Propagation of metric waves beyond optical range

Heightman, D.W.

Journal:

Journal of the British Institution of Radio Engineers

Year:

1950

Language:

english

File:

PDF, 1.34 MB

english, 1950

37

Printed circuit reliability and flammability

Heightman, D.W.

Journal:

Journal of the British Institution of Radio Engineers

Year:

1960

Language:

english

File:

PDF, 193 KB

english, 1960

38

A Transductor regulator for stabilized power supplies

Heightman, A.N.

Journal:

Journal of the British Institution of Radio Engineers

Year:

1960

Language:

english

File:

PDF, 1.81 MB

english, 1960

39

Component and valve reliability in domestic radio and television receivers

Heightman, D.W.

Journal:

Journal of the British Institution of Radio Engineers

Year:

1961

Language:

english

File:

PDF, 732 KB

english, 1961

40

Solar radio radiation

Heightman, Denis W., Cook, F.E., McCue, C.G.

Journal:

Radio and Electronic Engineer

Year:

1975

Language:

english

File:

PDF, 310 KB

english, 1975

41

Whither the british radio and television industry?

Heightman, Denis W.

Journal:

Radio and Electronic Engineer

Year:

1979

Language:

english

File:

PDF, 1.37 MB

english, 1979

42

Terminal Aziridines by α-Deprotonation/Electrophile Trapping of N-Protected Aziridine

Hodgson, David M., Hughes, Steven P., Thompson, Amber L., Heightman, Tom D.

Journal:

Organic Letters

Year:

2008

Language:

english

File:

PDF, 123 KB

english, 2008

43

High-Affinity Inhibitors of Human NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase: Mechanisms of Inhibition and Structure-Activity Relationships

Niesen, Frank H., Schultz, Lena, Jadhav, Ajit, Bhatia, Chitra, Guo, Kunde, Maloney, David J., Pilka, Ewa S., Wang, Minghua, Oppermann, Udo, Heightman, Tom D., Simeonov, Anton, Gay, Nick

Journal:

Year:

2010

Language:

english

File:

PDF, 1.41 MB

english, 2010

44

Application of a Recyclable Pseudoephedrine Resin in Asymmetric Alkylations on Solid Phase

Hutchison, Panee C., Heightman, Tom D., Procter, David J.

Journal:

Journal of Organic Chemistry

Year:

2004

Language:

english

File:

PDF, 256 KB

english, 2004

45

Synthesis and Biological Evaluation of JAHAs: Ferrocene-Based Histone Deacetylase Inhibitors

Spencer, John, Amin, Jahangir, Wang, Minghua, Packham, Graham, Alwi, Sharifah S. Syed, Tizzard, Graham J., Coles, Simon J., Paranal, Ronald M., Bradner, James E., Heightman, Tom D.

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 808 KB

english, 2011

46

Application of an ephedrine chiral linker in a solid-phase, ?asymmetric catch-release? approach to ?-butyrolactones

Kerrigan, Nessan J., Hutchison, Panee C., Heightman, Tom D., Procter, David J.

Journal:

Chemical Communications

Year:

2003

Language:

english

File:

PDF, 206 KB

english, 2003

47

WHSC1 links transcription elongation to HIRA-mediated histone H3.3 deposition

Sarai, Naoyuki, Nimura, Keisuke, Tamura, Tomohiko, Kanno, Tomohiko, Patel, Mira C, Heightman, Tom D, Ura, Kiyoe, Ozato, Keiko

Journal:

The EMBO Journal

Year:

2013

Language:

english

File:

PDF, 1.24 MB

english, 2013

48

Fragment-Based Discovery of 6-Azaindazoles As Inhibitors of Bacterial DNA Ligase

Howard, Steven, Amin, Nader, Benowitz, Andrew B., Chiarparin, Elisabetta, Cui, Haifeng, Deng, Xiaodong, Heightman, Tom D., Holmes, David J., Hopkins, Anna, Huang, Jianzhong, Jin, Qi, Kreatsoulas, Cons

Journal:

ACS Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.67 MB

english, 2013

49

Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery

Philpott, Martin, Yang, Jing, Tumber, Tony, Fedorov, Oleg, Uttarkar, Sagar, Filippakopoulos, Panagis, Picaud, Sarah, Keates, Tracy, Felletar, Ildiko, Ciulli, Alessio, Knapp, Stefan, Heightman, Tom D.

Journal:

Molecular BioSystems

Year:

2011

Language:

english

File:

PDF, 3.13 MB

english, 2011

50

A Structural View of the Action of Escherichia coli ( lac Z) β-Galactosidase †,‡

Juers, Douglas H., Heightman, Tom D., Vasella, Andrea, McCarter, John D., Mackenzie, Lloyd, Withers, Stephen G., Matthews, Brian W.

Journal:

Year:

2001

Language:

english

File:

PDF, 1.05 MB

english, 2001